Percodan
Generic Name: aspirin and oxycodone (AS pir in and ox i KOE done)
Brand Names: Endodan, Percodan, Roxiprin
What is Percodan?
Percodan contains a combination of aspirin and oxycodone. Aspirin is in a group of drugs called salicylates. It works by reducing substances in the body that cause pain, fever, and inflammation. Oxycodone is in a group of drugs called narcotic pain relievers.
Percodan is used to relieve moderate to severe pain.
Percodan may also be used for other purposes not listed here.
Important information about Percodan
Stop using Percodan and call your doctor at once if you have any symptoms of bleeding in your stomach or intestines. Symptoms include black, bloody, or tarry stools, and coughing up blood or vomit that looks like coffee grounds.
Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children.
Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Never share Percodan with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Avoid drinking alcohol while taking Percodan. It may increase your risk of stomach bleeding while taking aspirin.
Tell your doctor if Percodan seems to stop working as well in relieving your pain.
Before taking Percodan
Do not use Percodan if you are allergic to aspirin or oxycodone or to a non-steroidal anti-inflammatory drug (NSAID) such as Advil, Aleve, Motrin, Naprosyn, Orudis, Cataflam, Feldene, Indocin, Lodine, Mobic, Relafen, Toradol, Voltaren, and others. Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Never share Percodan with another person, especially someone with a history of drug abuse or addiction.
Aspirin should not be given to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Aspirin can cause a serious and sometimes fatal condition called Reye's syndrome in children. Do not use Percodan if you have a bleeding or blood clotting disorder such as hemophilia.
If you have any of these other conditions, your doctor may need to adjust the dose of Percodan or order special tests:
asthma or other breathing disorders;
liver or kidney disease;
a history of head injury or brain tumor;
epilepsy or other seizure disorder;
stomach or intestinal disorder, history of stomach ulcer or bleeding;
a pancreas disorder;
curvature of the spine; or
mental illness or a history of drug or alcohol addiction.
FDA pregnancy category D. Percodan can cause harm to an unborn baby, and breathing problems or addiction/withdrawal symptoms in a newborn. Taking aspirin during late pregnancy may cause bleeding in the mother or the baby during delivery. Do not take Percodan during pregnancy unless your doctor has told you to. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment. Aspirin and oxycodone can pass into breast milk and may harm a nursing baby. Do not use Percodan without telling your doctor if you are breast-feeding a baby.
See also: Percodan Infromation from Drugs.com pregnancy and breastfeeding warnings (in more detail)
Older adults may be more sensitive to the effects of Percodan.
How should I take Percodan?
Take Percodan exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking Percodan. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor. You may have withdrawal symptoms when you stop using Percodan after using it over a long period of time.
Do not stop using the medication suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely. If you need surgery, tell the surgeon ahead of time that you are using Percodan.
Store Percodan at room temperature away from moisture, heat, and light.
Keep track of the amount of Percodan used from each new bottle. Oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
See also: Percodan Infromation from Drugs.com dosage (in more detail)
What happens if I miss a dose?
Since Percodan is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Percodan can be fatal.
Overdose symptoms may include extreme drowsiness, pinpoint pupils, nausea, vomiting, diarrhea, confusion, ringing in your ears, cold or clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, coma, blue lips, shallow breathing, or no breathing.
What should I avoid while taking Percodan?
Percodan may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Ask a doctor or pharmacist before using any other over-the-counter cold, allergy, or pain medicine. Aspirin is contained in many combination medicines. Taking certain products together can cause you to get too much aspirin. Check the label to see if a medicine contains aspirin.
Avoid drinking alcohol. It may increase your risk of stomach bleeding while taking aspirin.
Percodan side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Percodan: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects while taking Percodan:
black, bloody, or tarry stools, coughing up blood or vomit that looks like coffee ground;
shallow breathing, slow heartbeat;
fast heart rate;
feeling light-headed, fainting;
confusion, hallucinations;
easy bruising or bleeding; or
problems with urination.
Less serious Percodan side effects may include:
headache, dizziness, drowsiness;
heartburn, nausea, vomiting, upset stomach, bloating, gas, constipation, diarrhea;
feeling dizzy or drowsy;
headache;
sweating;
ringing in your ears; or
dry mouth.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
See also: Percodan Infromation from Drugs.com side effects (in more detail)
What other drugs will affect Percodan?
Before using Percodan, tell your doctor if you regularly use other medicines that make you sleepy or could slow your breathing (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by Percodan.
Tell your doctor about all other medicines you use, especially:
acetazolamide (Diamox);
a diuretic (water pill);
methotrexate (Rheumatrex, Trexall);
steroids (prednisone and others);
a blood thinner such as warfarin (Coumadin);
a bronchodilator (such as Atrovent, Spiriva);
atropine (Donnatal), dimenhydrinate (Dramamine), or scopolamine (Transderm-Scop);
insulin or diabetes medications that you take by mouth;
an ACE inhibitor such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;
a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;
bowel or bladder medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin), tolterodine (Detrol) and others; or
an NSAID such as ibuprofen (Motrin, Advil), diclofenac (Cataflam, Voltaren), etodolac (Lodine), indomethacin (Indocin), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
This list is not complete and other drugs may interact with Percodan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
More Percodan Infromation from Drugs.com resources
Percodan Infromation from Drugs.com Side Effects (in More Detail)
Percodan Infromation from Drugs.com Dosage
Percodan Infromation from Drugs.com Use in Pregnancy & Breastfeeding
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Percodan Infromation from Drugs.com Drug Interactions
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Where can I get more information?
Your pharmacist can provide more information about Percodan.
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